Strength, Persistence and Affordability
Why We Need Systemic Enzymes
The word “systemic” means body
wide. Systemic enzymes are those that operate not just for
digestion but throughout your body in every system and organ.
But let’s take first things first, what is an enzyme?
An enzyme is a biocatalyst - something that
makes something else work or work faster. Chemical reactions
are generally slow things, enzymes speed them up. Without
enzymes the chemical reactions that make up our life would
be too slow for life as we know it. (As slow as sap running
down a tree in winter). For life to manifest as we know it,
enzymes are essential to speed up the reactions. We have
roughly some 3000 enzymes in our bodies and that results
in over 7000 enzymic reactions. Most of these enzymes are
derived or created from what we think of as the protein digesting
enzymes. But while digestion is an important part of what
enzymes do, it's almost the absolute last function.
First and foremost these body wide proteolytic
(protein eating) enzymes have the following actions:
Inflammation is a reaction by the
immune system to an irritation. Let’s say you
have an injured right knee. The immune system, sensing
the irritation the knee is undergoing, creates a
protein chain called a Circulating Immune Complex
(CIC for short), tagged specifically for that right
knee. (The Nobel Prize in biology was won in 1999
by a scientist who discovered this tagging mechanism).
This CIC floats down to the right knee and causes
pain, redness and swelling; the classic earmarks
for inflammation. This at first is a beneficial reaction
because it warns us that a part of ourselves is hurt
and needs attention. But, inflammation is self-perpetuating;
itself creating an irritation that the body makes
CIC’s to in response!
At this point, most people turn to
their medicine chest and take a couple of Non Steroidal
Anti-Inflammatory drugs (NSAIDs) like Aspirin, Ibuprofen,
Celebrex, Vioxx, etc. And the problem with that is:
NSAID's work by keeping the body from making all CIC's!!!
This ignores the fact that some CIC’s are vital
to life, like those that maintain the lining of the
intestines and those that keep the kidneys functioning!
Not to mention the fact that the NSAID’s, along
with acetaminophen, are highly toxic to the liver.
Every year 20,000 Americans die from these over the
counter drugs and another 100,000 will wind up in the
hospital with liver damage, kidney damage or bleeding
intestines from the side effects of these drugs. (4,5).
This is where systemic enzyme use is so important.
Systemic Enzymes are the first line
of defense against inflammation. (1,2,3). Systemic
enzymes are perfectly safe and free of dangerous side
effects and they have no LD-50, or toxic dose. (6).
Best of all systemic enzymes can tell the difference
between the good CIC’s and the bad ones because
hydrolytic enzymes are lock and key mechanisms and
their "teeth" will only fit over the bad
CIC’s. So instead of preventing the creation
of all CIC’s, systemic enzymes just “eat” the
bad ones and in so doing lower inflammation everywhere.
With that, pain is lowered also.
Systemic Enzymes eat scar tissue
and fibrosis. (7). Fibrosis is scar tissue and most
doctors learn in anatomy that it is fibrosis that
eventually kills us all.
Let me explain: As we age, which starts
at 27, we have a diminishing of the bodies’ output
of enzymes. This is because we make a finite amount
of enzymes in a lifetime and we use up a good deal
of them by the time we are 27. At that point the body
knows that if it keeps up that rate of consumption
we’ll run out of enzymes and be dead by the time
we reach our 40’s. (Cystic Fibrosis patients
who have virtually no enzyme production to speak of,
even as children usually don’t make it past their
20’s before they die of the restriction and shrinkage
in the lungs from the formation of fibrosis or scar
So, our body in it's wisdom begins
to dole out our enzymes with an eyedropper instead
of with a tablespoon; as a result, the repair mechanism
of the body goes out of balance and has nothing to
reduce the over abundance of fibrin it deposits in
nearly every thing from simple cuts, to the inside
of our internal organs and blood vessels. This is when
most women begin to develop things like fibrocystic
breast disease, uterine fibroids, endometriosis, and
we all grow arterial sclerotic (meaning scar tissue)
plaque, and have fibrin beginning to spider web its
way inside of our internal organs reducing their size
and function over time. This is why as we age our wounds
heal with thicker, less pliable, weaker and very visible
If we replace the lost enzymes we
can control and reduce the amount of scar tissue and
fibrosis our bodies have. As physicians in the US are
now discovering, even old scar tissue can be “eaten
away” from surgical wounds, pulmonary fibrosis,
kidney fibrosis and even keloids years after their
formation. Medical doctors in Europe and Asia have
known this and have used orally administered enzymes
for these situations for over 40 years!
The blood is not only the river
of life, it is also the river through which the cells
and organs dispose of their garbage and dead material.
Enzymes improve circulation by eating the excess
fibrin that causes blood to sometimes get as thick
as catsup or yogurt, creating the perfect environment
for the formation of clots. All of this material
is supposed to be cleared by the liver on its "first
pass", or the first time it goes through but
given the sluggish and near toxic or toxic states
of everyone's liver these days that seldom happens.
So the sludge remains in the blood waiting for the
liver to have enough free working space and enough
enzymes to clean the trash out of the blood. This
can take days, and in some cases, weeks! (8).
When systemic enzymes are taken, they
stand ready in the blood and take the strain off of
the liver by:
- Cleaning excess fibrin from the blood and reducing
the stickiness of blood cells. These two actions
minimize the leading causes of stroke and heart
attack causing blood clots. (8).
- Breaking dead material down small enough that
it can immediately pass into the bowel. (8).
- Cleanse the FC receptors on the white blood cells
improving their function and availability to fight
off infection. (9). And here we come to the only
warning we have to give concerning the use of systemic
enzymes - don't use the product if you are a hemophiliac
or are on prescription blood thinners like Coumadin
and Heparin, without direct medical supervision.
The enzymes cause the drugs to work better so there
is the possibility of thinning the blood too much.
Enzymes are adaptogenic seeking to restore a steady
state to the body. (9). When the immune system is
running low we become susceptible to infectious disease,
when it’s cranked up too high then the system
creates antibodies that attack it's own tissues as
are seen in the auto immune diseases of MS, Rheumatoid
Arthritis, and Lupus. Here the enzymes will tone
down immune function and eat away at the antibodies
the immune system is making to attack its bodies
and Bacteria Fighting
Viruses harm us by replicating in
our bodies. To do this a virus must bond itself to
the DNA in our cells through the medium of its exterior
protein cell wall. Anything that disrupts that cell
wall inhibits the ability of viral replication by
rendering individual viruses inert. (10,11). Systemic
enzymes can tell the difference between the proteins
that are supposed to be in your body and those that
are foreign or not supposed to be there, (again the
enzyme lock and key mechanism). Serrapeptase has
the strongest protein eating effect of any commercially
available enzyme and can be of help in combating
Systemic Enzymes also have been found
to have mild anti-bacterial properties. A bacteria
is a foreign protein (exogenous). Proteolytic enzymes
eat exogenous proteins in the body.
One note: many in the States have
learned in school that enzymes are too big a protein
to be absorbed through the gut. The pioneering research
done in the US by Dr. Max Wolf (MD & PhD x7) at
Columbia University in the 40’s through the 70’s
has not made it to the awareness of most doctors. There
are currently over 200 peer reviewed research articles
dealing with the absorption, utilization and therapeutic
action of orally administered systemic enzymes. A search
through Pub Med using the key words: serrapeptase,
papain, bromelain, trypsin, chymo trypsin, nattokinase
and systemic enzyme will yield some of the extensive
work. Systemic enzymes now have a 4 decade plus history
of widespread medical use in central Europe and Japan.
1) Carroll A., R.: Clinical examination of an enzymatic
anti-inflammatory agent in emergency surgery. Arztl.
Praxis 24 (1972), 2307.
2) Mazzone A, et al.: Evaluation of Serratia peptidase
in acute or chronic
inflammation of otorhinolaryngology pathology: a multicentre,
randomized trial versus placebo. J Int Med Res. 1990;
3) Kee W., H. Tan S, L., Lee V. Salmon Y. M.: The treatment
of breast engorgement with Serrapeptase: a randomized
double blind controlled trial. Singapore Med J. 1989:30(l):48-54.
4) Celebrex article Wall Street Journal 19 April 1999.
5) No author listed: Regular Use of Pain Relievers
Can Have Dangerous Results. Kaleidoscope Interactive
News, American Medical Association media briefing.
July 24, 1997.
6) Enzymes ñ A Drug of the Future, Prof. Heinrich
Wrba MD and Otto Pecher MD. Published 1993 Eco Med.
7) Kakinumu A. et al.: Regression of fibrinolysis in
scalded rats by administration of serrapeptase. Biochem.
8) Ernst E., Matrai A.: Oral Therapy with proteolytic
enzymes for modifying blood rheology. Klin Wschr. 65
9) Kunze R., Ransberger K., et at: Humoral immunomodulatory
capasity of proteases in immune complex decomposition
and formation. First International symposium on combination
therapies, Washington, DC, 1991.
10) Jager H.: Hydrolytic Enzymes in the therapy of
HIV disease. Zeitschr. Allgemeinmed., 19 (1990), 160.
11) Bartsch W.: The treatment of herpes zoster using
proteolytic enzymes. Der Informierte Arzt. 2 (1974),
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